Table 5 OS and PFS (ITP group)
Median OS (months) | Median PFS (months) | |||||||
|---|---|---|---|---|---|---|---|---|
Protein Expression | Low | High | P-value | Low | High | P-value | ||
ERCC1 | 21.4 | 10.5 | 0.049 | 8.2 | 6 | 0.558 | ||
COX2 | 17.7 | 10.5 | 0.363 | 7.9 | 6 | 0.895 | ||
Tubulin B3 | 11.9 | 16.4 | 0.529 | 8.2 | 7.9 | 0.74 | ||
CD4 | 11.9 | 25.5 | 0.397 | 6.6 | 10.1 | 0.113 | ||
CD8 | 11.9 | 5.4 | 0.476 | 7.9 | 1.2 | 0.707 | ||
SNPs | ||||||||
MDR1 C3435T | CC | TT | CT | P-value | CC | TT | CT | P-value |
3.4 | 11.9 | 11.7 | 0.467 | 1.8 | 8.8 | 8.1 | 0.484 | |
MDR1 G2677 T | GG | TT | GT | GG | TT | GT | ||
11.9 | 2.9 | 21.9 | 0.647 | 6.5 | 2.9 | 8.6 | 0.494 | |
ERCC1C8092A | AA | CC | CA | AA | CC | CA | ||
25.2 | 11.9 | 11.9 | 0.664 | 10.2 | 7.9 | 6.5 | 0.702 | |
ERCC1 N118 N | CC | TT | CT | CC | TT | CT | ||
11.6 | 21.6 | 5.6 | 0.401 | 8.2 | 10.1 | 3.6 | 0.003 | |