Fig. 4

PAK1 knockout increased the numbers of CD3⁺ and B220⁺ follicles in the spleen of APC^∆14/+ mice. The spleens of with PAK1 WT APC^∆14/+ mice (n = 10) or PAK1 KO APC^∆14/+ mice (n = 12) were immunohistochemically stained with antibodies against CD3 or B220, and numbers of positively stained follicles were counted. *, p < 0.05 compared to PAK1 WT APC^∆14/+ mice