Fig. 1
Bmi1 and PAK1 expression are positively correlated in the intestinal tumours of APC∆14/+ mice. Both normal (N) and tumour (T) tissues were dissected from colon/rectum (a, b) or small intestine (c, d) of APC∆14/+ mice. The protein concentrations of Bmi1 and PAK1 were determined by Western blot, normalised to GAPDH, and averaged over 3 replicate blots (a, c). Regression lines for the correlation of Bmi1 and PAK1 were plotted using the program Sigma Plot 12 (b, d). R2: regression coefficients for normal and tumour samples. m: male, *, p < 0.05; **, p < 0.01 from samples of tumour tissues compared with samples of adjacent normal tissues