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Table 4 Enriched MsigDB Hallmark genesets

From: Identifying global expression patterns and key regulators in epithelial to mesenchymal transition through multi-study integration

Geneset p-values oddsratio FDR Genes in set
HALLMARK Epithelial mesenchymal transition 9.84E-33 18.3575636 4.92E-31 CD59, CDH11, CDH2, COL1A1, COL1A2, COL4A2, COL5A1, COL6A3, CTGF, CYR61, DAB2, DPYSL3, EDIL3, EMP3, ENO2, FAP, FBN1, FBN2, FERMT2, GEM, GJA1, GREM1, LGALS1, LOX, MMP14, MMP2, PCOLCE, PCOLCE2, PLAUR, PLOD1, PMP22, POSTN, SERPINE1, SERPINE2, SLIT2, SPARC, SPOCK1, TGFB1, TIMP1, VCAN, VIM, WNT5A
HALLMARK Estrogen response late 9.36E-06 4.332224532 0.00019652 ALDH3A2, ASS1, CDH1, CELSR2, LLGL2, LSR, MAPK13, PLXNB1, RAPGEFL1, SCNN1A, SLC22A5, SLC27A2, ST14, TOB1, TRIM29
HALLMARK Apical junction 1.18E-05 4.516129032 0.00019652 AKT3, CDH1, CDH11, CLDN7, FBN1, GRB7, JAM3, JUP, MAPK13, MMP2, MPZL2, PVRL3, SLIT2, VCAN
HALLMARK UV response dn 8.16E-05 4.23768997 0.001019448 AKT3, COL1A1, COL1A2, CYR61, DAB2, FZD2, GJA1, HAS2, KCNMA1, MAP1B, PMP22, SERPINE1
HALLMARK Estrogen response early 0.000247578 3.495078664 0.002475779 AQP3, CELSR2, CLDN7, ELF3, GJA1, KRT15, PMAIP1, RAPGEFL1, SCNN1A, SLC22A5, SLC27A2, TOB1, WWC1
HALLMARK Hypoxia 0.000436298 3.276838008 0.003635818 AKAP12, CHST2, COL5A1, CTGF, CYR61, ENO2, ETS1, HMOX1, KDELR3, LOX, PLAUR, SERPINE1, SRPX
HALLMARK Inflammatory response 0.000679488 3.786760716 0.004246802 CD70, CHST2, EMP3, FZD5, HAS2, HRH1, MMP14, PLAUR, SERPINE1, TIMP1
HALLMARK KRAS signaling up 0.00061698 3.554348835 0.004246802 AKAP12, EPB41L3, ETS1, GFPT2, GNG11, JUP, MAP7, MPZL2, PLAUR, TMEM158, TRIB2
HALLMARK Angiogenesis 0.003822541 7.2 0.02123634 JAG2, POSTN, TIMP1, VCAN
HALLMARK Complement 0.00451196 3.068992514 0.022559801 CD59, COL4A2, CTSD, MMP14, PLAUR, SERPINE1, TIMP1, TIMP2, ZEB1
HALLMARK Myogenesis 0.00594623 2.929880329 0.027028319 COL1A1, COL4A2, COL6A3, ERBB3, MEF2C, NCAM1, PDLIM7, SPARC, TGFB1
HALLMARK TGF beta signaling 0.010673511 4.097902098 0.044472964 BCAR3, CDH1, SERPINE1, SMURF2, TGFB1