Fig. 1
![Fig. 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12885-017-3413-3/MediaObjects/12885_2017_3413_Fig1_HTML.gif)
Epithelial to Mesenchymal Transition. During EMT, non-motile epithelial cells trans differentiate to mesenchymal cells with increased migratory potential. During this, cells show decreased expression epithelial specific genes that include E-cadherin, OVOL1 and ESRP1. At the same time, expression of mesenchymal genes such as N-cadherin, VIM and ZEB1 increases