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Fig. 2 | BMC Cancer

Fig. 2

From: Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters

Fig. 2

Longitudinal flow cytometry data on DC across six cycles of chemoimmunotherapy, detailing changes in mean fluorescence intensity (MFI) relating to expression levels of CD40 or HLA-DR in BDCA-1, BDCA-2 and BDCA-3 DC subsets. Left-hand panels show observed values from individual patients, together with their empirical means (solid line). Right hand panels show results of fitting a linear mixed model; a linear trend over time and additive treatment effects of the day of the treatment yield the corresponding population average curves. (P-values: * <0.05, ** <0.01, *** <0.001, **** < 0.0001)

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BMC Cancer

ISSN: 1471-2407

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