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Fig. 2 | BMC Cancer

Fig. 2

From: Metabolic targeting of HIF-dependent glycolysis reduces lactate, increases oxygen consumption and enhances response to high-dose single-fraction radiotherapy in hypoxic solid tumors

Fig. 2

a and b show Western Blot analysis of HIF-1α protein levels from ME180 HIF-WT (DOX-) and HIF-1 KD (DOX+) cells and FaDu HIF-WT (WT), empty vector control (EV) HIF-1 KD (HIF-1 KD) cells in air (0 h) and 0.2% oxygen (8, 24 h ME180; 24 h FaDu). c shows RTPCR for CAIX, which confirms downstream inhibition of CAIX mRNA transcription following HIF-1 protein knockdown (HKG, housekeeping genes)

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