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Table 1 Association of PKCα and NF-κB p65 expression with clinicopathologic characteristics of the bladder cancer patients

From: Protein kinase C-α (PKCα) modulates cell apoptosis by stimulating nuclear translocation of NF-kappa-B p65 in urothelial cell carcinoma of the bladder

Parameters Group No. of cases P-value
PKCα NF-κB p65
Gender Male 17 (56.7%) 0.214 0.453
Age (years) ≥60 19 (63.3%) 0.371 0.284
Histological grade High grade 21 (70%) < 0.01** < 0.01**
Muscle invasion Positive 20 (66.7%) <0.01** <0.01**
Distant metastases Positive 4 (13.3%) 0.124 0.073
Lymphatic invasion Positive 6 (20%) <0.05* < 0.05*
  1. PKCα and p65 expressions were measured by IHC staining, PKCα or p65 positive cell percentages per HPF were counted and statistically compared between two groups. Student’s T test was used to conduct the statistical analysis. *P < 0.05, **P < 0.01