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Table 1 Inclusion criteria

From: Internet-based perioperative exercise program in patients with Barrett’s carcinoma scheduled for esophagectomy [iPEP - study] a prospective randomized-controlled trial

# Inclusion criteria
1. Histologically proven adenocarcinoma of the esophagus or adenocarcinoma of the esophagogastric junction type I-II according to Siewert’s classification, clinical stages IIB-IIIC (T3/T4 and/or N+; M0) according to UICC, 7th edition
2. Male
3. Age between 18 and 75 years
4. Resectable stage according to discussion in the local multidisciplinary tumor board (MDT) of the participating centers and patient medically fit for multimodality therapy (ECOG performance status at least 1 or better, no severe impairment of cardiac, renal, hepatic, endocrine, bone marrow and cerebral functions)
5. Planned abdomino-thoracic esophagectomy with gastric pull-up and intrathoracic or cervical anastomosis
6. Cognitive ability of the patient to understand the perioperative program and to participate actively [40, 41]