Table 1 Correlation of RCE1 and p-p38 protein expression with clinicopathological parameters
From: Reduced RCE1 expression predicts poor prognosis of colorectal carcinoma
Characteristics | n | RCE1 | P-value | P-p38 | P-value | ||
|---|---|---|---|---|---|---|---|
Low | High | Low | High | ||||
Gender | |||||||
Female | 96 | 36 (37.5%) | 60 (62.5%) | 0.113 | 43 (44.8%) | 53 (55.2%) | 0.190 |
Male | 148 | 72 (48.6%) | 76 (51.4%) | 80 (54.1%) | 68 (45.9%) | ||
Age (y) | |||||||
> 60 | 105 | 40 (38.1%) | 65 (61.9%) | 0.118 | 51 (48.6%) | 54 (51.4%) | 0.698 |
≤ 60 | 139 | 68 (48.9%) | 71 (51.1%) | 72 (51.8%) | 67 (48.2%) | ||
CEA (ng/ml) | |||||||
> 5 | 116 | 63 (54.3%) | 53 (45.7%) | 0.003 | 67 (58.0%) | 49 (42.0%) | 0.030 |
≤ 5 | 128 | 45 (35.2%) | 83 (64.8%) | 56 (43.8%) | 72 (56.2%) | ||
CA19–9 (U/ml) | |||||||
> 37 | 59 | 30 (50.8%) | 29 (49.2%) | 0.107 | 30 (50.8%) | 29 (49.2%) | 0.021 |
≤ 37 | 185 | 78 (42.2%) | 107 (57.8%) | 93 (50.3%) | 92 (49.7%) | ||
Location | |||||||
colon | 121 | 56 (46.3%) | 65 (53.7%) | 0.797 | 64 (52.9%) | 57 (47.1%) | 1.000 |
Rectum | 123 | 51 (41.5%) | 71 (58.5%) | 59 (48.0%) | 64 (52.0%) | ||
Depth of invasion | |||||||
T1/T2 | 58 | 15 (25.9%) | 43 (74.1%) | 0.001 | 18 (31.0%) | 40 (69.0%) | 0.001 |
T3/T4 | 186 | 93 (48.7%) | 93 (51.3%) | 105 (56.5%) | 81 (43.5%) | ||
Histological grade | |||||||
I/II | 214 | 95 (44.4%) | 119 (55.6%) | 1.000 | 108 (50.5%) | 106(49.5%) | 1.000 |
III | 30 | 13 (43.3%) | 17 (56.7%) | 15 (50%) | 15(50%) | ||
Node stage | |||||||
N0 | 156 | 58 (37.2%) | 98 (62.8%) | 0.000 | 79 (50.6%) | 77 (49.4%) | 0.790 |
N1 | 59 | 26 (44.1%) | 33 (55.9%) | 28 (47.5%) | 31 (52.5%) | ||
N2 | 29 | 24 (82.8%) | 5 (17.2%) | 16 (55.2%) | 13 (44.8%) | ||
TNM stage | |||||||
I | 48 | 11 (22.9%) | 37 (77.1%) | 0.001 | 17 (35.4%) | 37 (64.6%) | 0.04 |
II | 108 | 48 (44.4%) | 60 (55.6%) | 62 (57.4%) | 46 (42.6%) | ||
III | 88 | 49 (56.7%) | 39 (43.3%) | 44 (50%) | 44 (50%) | ||