Skip to main content

Table 2 Results of univariate analysis for possible independent variables associated with death and EFS

From: What is the impact of local control in Ewing sarcoma: analysis of the first Brazilian collaborative study group – EWING1

Variables EFS LF
5-year CI HR (95% CI) p 5-year CI HR (95% CI) p
All patients 62.1% - - 6.9% - -
Age group
  ≤ 15 years 68.0% 1.00   4.6% 1.00  
  > 15 years 47.6% 2.00 (0.91–4.41) 0.087 13.8% 3.11 (0.44–22.1) 0.257
Sex
 Male 64.0% 1.00   9.1% 1.00  
 Female 58.6% 1.30 (0.60–2.83) 0.513 4.8% 0.58 (0.06–5.53) 0.575
Risk group
 Low 73.7% 1.00   5.6% 1.00  
 High 48.2% 1.74 (0.80–3.80) 0.163 8.3% 1.33 (0.19–9.41) 0.779
Tumor size
  ≤ 8 cm 61.1% 1.00   -- -- --
  > 8 cm 58.1% 1.07 (0.41–2.76) 0.892 -- -- --
Necrosis Index
  ≤ 95% 60.7% 1.38 (0.54–3.57) 0.503 5.6% 0.41 (0.04–4.52) 0.466
  > 95% 71.3% 1.00   10.5% 1.00  
LDH
  ≥ 1.5 x ULN 51.3% 1.11 (0.44–2.77) 0.832 15.4% 6.04 (0.55–66.7) 0.142
  < 1.5 x ULN 63.1% 1.00   2.4% 1.00  
Pelvic location
 Yes 41.1% 1.47 (0.55–3.90) 0.440 -- -- --
 No 66.7% 1.00   -- -- --
Radiation dose - 0.99 (0.98–1.01) 0.560 - 0.98 (0.86–1.12) 0.796
  1. EFS event-free survival, LF local failure, CI cumulative incidence, HR hazard ratio; 95% CI, 95% confidence interval, LDH lactate dehydrogenase, ULN upper limit of normal