Table 1 Characteristics of the Sample according to the Local Control Modality
Variables | Total sample | Local Control Modality | p | ||
|---|---|---|---|---|---|
Surgery | Surgery + Radiotherapy | Radiotherapy | |||
n (%) | n (%) | n (%) | n (%) | ||
All patients | 73 (100) | 47 (64.4) | 13 (17.8) | 13 (17.8) | |
Age group | 0.753 | ||||
≤ 15 years | 51 (69.9) | 34 (72.3) | 8 (61.5) | 9 (69.2) | |
> 15 years | 22 (30.1) | 13 (27.7) | 5 (38.5) | 4 (30.8) | |
Sex | 0.035 | ||||
Male | 45 (61.6) | 33 (70.2)a | 4 (30.8) | 8 (61.5) | |
Female | 28 (38.4) | 14 (29.8) | 9 (69.2)a | 5 (38.5) | |
Risk group | <0.001 | ||||
Low | 38 (52.1) | 33 (70.2)a | 5 (38.5) | 0 (0.0) | |
High | 35 (47.9) | 14 (29.8) | 8 (61.5) | 13 (100)a | |
Tumor size | 0.124 | ||||
≤ 8 cm | 18/45 (40.0) | 10/31 (32.3) | 4/9 (44.4) | 4/5 (80.0) | |
> 8 cm | 27/45 (60.0) | 21/31 (67.7) | 5/9 (55.6) | 1/5 (20.0) | |
Necrosis Index | 1.000 | ||||
≤ 95% | 28/50 (56.0) | 23/42 (54.8) | 5/8 (62.5) | NA | |
> 95% | 22/50 (44.0) | 19/42 (45.2) | 3/8 (37.5) | NA | |
LDH | 0.052 | ||||
≥ 1.5 x ULN | 15/68 (22.1) | 6/45 (13.3) | 4/10 (40.0) | 5/13 (38.5) | |
< 1.5 x ULN | 53/68 (77.9) | 39/45 (86.7) | 6/10 (60.0) | 8/13 (61.5) | |
Recurrence | 0.509 | ||||
No | 53/68 (77.9) | 34/46 (73.9) | 10/12 (83.3) | 9/10 (90.0) | |
Local | 4/68 (5.9) | 3/46 (6.5) | 0/12 (0.0) | 1/10 (10.0) | |
Systemic | 11/68 (16.2) | 9/46 (19.6) | 2/12 (16.7) | 0/10 (0.0) | |
Site location | <0.001 | ||||
Spine | 6 (8.2) | 0 (0.0) | 1 (7.7) | 5 (38.5)a | |
Chest wall | 10 (13.7) | 6 (12.8) | 4 (30.8)a | 0 (0.0) | |
Pelvis | 10 (13.7) | 3 (6.4) | 2 (15.4) | 5 (38.5)a | |
Proximal extremity | 21 (28.8) | 17 (36.2)a | 2 (15.4) | 2 (15.4) | |
Distal extremity | 22 (30.1) | 19 (40.4)a | 3 (23.1) | 0 (0.0) | |
Other | 4 (5.5) | 2 (4.3) | 1 (7.7) | 1 (7.7) | |
Radiation dose (Gy)b | 50.4 (45–55.8) | NA | 50.4 (45–54.9) | 50.4 (45–55.8) | 0.801 |