Table 3 MBL codon 54 G > A polymorphism and the risk of gastroduodenal diseases
Genotype | Disease group | Unadjusted OR (95% CI) by univariate analysis | p | Adjusted OR (95% CI) by multivariate analysis | p |
|---|---|---|---|---|---|
G/A (heterozygote) | Hp(+) NAG (n = 49) | 0.93 (0.56–1.55) | 0.7828 | 1.02 (0.59–1.75) | 0.9466 |
Hp(+) mild AG (n = 27) | 1.24 (0.66–2.34) | 0.5074 | 1.16 (0.60–2.26) | 0.6527 | |
Hp(+) severe AG (n = 37) | 1.38 (0.76–2.52) | 0.2937 | 1.16 (0.61–2.18) | 0.6498 | |
Hp(−) DU(n = 3) | 1.23 (0.27–5.66) | 0.7938 | 1.21 (0.26–5.71) | 0.8082 | |
Hp(+) DU (n = 73) | 1.19 (0.76–1.85) | 0.4450 | 1.24 (0.78–1.99) | 0.3605 | |
Hp(−) GC(n = 46) | 1.16 (0.65–2.04) | 0.6170 | 1.11 (0.61–2.00) | 0.7356 | |
Hp(+) GC (n = 122) | 0.85 (0.55–1.31) | 0.4566 | 0.85 (0.54–1.34) | 0.7356 | |
A/A (mutant) | Hp(+) NAG (n = 7) | 0.95 (0.33–2.74) | 0.9255 | 1.19 (0.39–3.61) | 0.7561 |
Hp(+) mild AG (n = 5) | 0.36 (0.04–2.89) | 0.3332 | 0.33 (0.04–2.81) | 0.3126 | |
Hp(+) severe AG (n = 9) | 0.64 (0.13–3.09) | 0.5822 | 0.61 (0.12–3.12) | 0.5560 | |
Hp(−) DU (n = 1) | 1.25(0.32–5.88) | 0.9521 | 1.24(0.31–5.77) | 0.9434 | |
Hp(+) DU (n = 14) | 0.43 (0.13–1.43) | 0.1697 | 0.45 (0.13–1.55) | 0.2031 | |
Hp(−) GC (n = 7) | 1.51 (0.52–4.42) | 0.4543 | 1.93 (0.63–5.89) | 0.2484 | |
Hp(+) GC (n = 27) | 0.88 (0.36–2.15) | 0.7762 | 1.10 (0.43–2.79) | 0.8496 | |
G/A + A/A (A carrier) | Hp(+) NAG (n = 56) | 0.93 (0.57–1.52) | 0.7820 | 1.04 (0.62–1.75) | 0.8774 |
Hp(+) mild AG (n = 32) | 1.12 (0.60–2.09) | 0.7239 | 1.05 (0.55–2.00) | 0.8893 | |
Hp(+) severe AG (n = 46) | 1.28 (0.71–2.29) | 0.4103 | 1.09 (0.59–2.01) | 0.7929 | |
Hp(−) DU (n = 4) | 1.06 (0.23–4.87) | 0.9421 | 1.06 (0.23–4.98) | 0.9386 | |
Hp(+) DU (n = 87) | 1.08 (0.71–1.66) | 0.7110 | 1.13 (0.72–1.78) | 0.5868 | |
Hp(−) GC (n = 53) | 1.20 (0.70–2.07) | 0.5008 | 1.19 (0.68–2.09) | 0.5480 | |
Hp(+) GC (n = 149) | 0.85 (0.57–1.29) | 0.4488 | 0.88 (0.57–1.35) | 0.5528 |