Fig. 2

Kaplan-Meier plots for fibrosarcoma- and mammary tumour-bearing mice receiving DXR HCl liposome injections or placebo. The figure shows data for: a syngeneic fibrosarcoma-bearing mice receiving 9 mg/kg SPIL DXR HCl liposome injection (n = 11), reference DXR HCl liposome injection (n = 15) or placebo (n = 15); b MX-1-bearing mice receiving 1.5 mg/kg SPIL or reference DXR HCl liposome injection, or placebo (n = 10 in each group); c MX-1-bearing mice receiving 3 mg/kg SPIL or reference DXR HCl liposome injection, or placebo (n = 10 in each group); and d MX-1-bearing mice receiving 6 mg/kg SPIL or reference DXR HCl liposome injection, or placebo (n = 10 in each group). Survival was estimated using the Kaplan-Meier method, and differences were analysed by log-rank test. Abbreviations: DXR, doxorubicin; HCl, hydrochloride; SPIL, Sun Pharmaceutical Industries Ltd.