Fig. 3
From: GABPA predicts prognosis and inhibits metastasis of hepatocellular carcinoma
GABPA positively regulated E-cadherin expression. a The protein and mRNA level of E-cadherin were significantly downregulated in BEL-7402-ShGABPA compared with BEL-7402-ShCtrl. b E-cadherin protein and mRNA levels were increased moderately when GABPA was overexpressed in Huh7 cells. c Immunohistochemical staining of GABPA and E-cadherin in four representative HCC clinical tissues. Spearman correlation analysis showed that GABPA expression was positively correlated with E-cadherin. Negative controls were prepared using non-immune rabbit IgG at the same dilution as the primary antibody in normal and tumor samples. d GABPA mRNA level in HCC tissues was positively associated with E-cadherin. (*P < 0.05; **P < 0.01)