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Table 2 Multivariate Cox regression models for progression-free and disease-specific survival

From: Glyoxalase 1 expression is associated with an unfavorable prognosis of oropharyngeal squamous cell carcinoma

  Progression-free survival Disease-specific survival
Risk factor HR 95% CI p-value HR 95% CI p-value
T status
T3–4 vs T1–21
1.282 0.749–2.197 0.365 1.230 0.667–2.268 0.508
N status
N+ vs N01
1.655 0.804–3.409 0.171 2.435 1.023–5.796 0.044
Clinical staging
IV vs I-III1
1.516 0.771–2.983 0.228 1.702 0.778–3.722 0.183
Tobacco
current vs never/former1
2.315 1.174–4.564 0.015 1.732 0.876–3.426 0.114
HPV status2
Non-related vs related1
0.412 0.200–0.849 0.016 0.356 0.157–0.805 0.013
Subgroup
GLO1high/nuc vs GLO1others, 1
1.784 1.054–3.018 0.031 1.791 1.037–3.094 0.037
  1. HR Hazard ratio, CI confidence interval, 1 reference group, 2 related = viral DNA + RNA + , non-related = viral DNA + RNA or viral DNA according to [20]
  2. Significant results (p <0.05) (including the HR, 95% CI) are marked in boldface