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Table 2 Multivariate Cox regression models for progression-free and disease-specific survival

From: Glyoxalase 1 expression is associated with an unfavorable prognosis of oropharyngeal squamous cell carcinoma

 

Progression-free survival

Disease-specific survival

Risk factor

HR

95% CI

p-value

HR

95% CI

p-value

T status

T3–4 vs T1–21

1.282

0.749–2.197

0.365

1.230

0.667–2.268

0.508

N status

N+ vs N01

1.655

0.804–3.409

0.171

2.435

1.023–5.796

0.044

Clinical staging

IV vs I-III1

1.516

0.771–2.983

0.228

1.702

0.778–3.722

0.183

Tobacco

current vs never/former1

2.315

1.174–4.564

0.015

1.732

0.876–3.426

0.114

HPV status2

Non-related vs related1

0.412

0.200–0.849

0.016

0.356

0.157–0.805

0.013

Subgroup

GLO1high/nuc vs GLO1others, 1

1.784

1.054–3.018

0.031

1.791

1.037–3.094

0.037

  1. HR Hazard ratio, CI confidence interval, 1 reference group, 2 related = viral DNA + RNA + , non-related = viral DNA + RNA or viral DNA according to [20]
  2. Significant results (p <0.05) (including the HR, 95% CI) are marked in boldface