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Table 1 Clinico-pathological features of the patients included in the study

From: Insulin-like growth factor 1 receptor affects the survival of primary prostate cancer patients depending on TMPRSS2-ERG status

Parameter qRT-PCR (n = 270) IHC (n = 239)
No. Pts % No. Pts %
Age
 ≤ 55 15 5.6 12 5
 56-65 81 30 72 30.1
 66-75 138 51.1 122 51
 > 75 36 13.3 33 13.8
Gleason-sp
 2-6 109 40.4 87 36.4
 7 129 47.8 123 51.5
 Greater than 7 32 11.9 29 12.1
PSA (ng/ml)
 10 or less 155 57.6 133 55.9
 10-20 74 27.5 69 29
 Greater than 20 40 14.9 36 15.1
cT
 cT2b or less 248 92.2 219 92
 cT3a or greater 21 7.8 19 8
pT
 pT2 or less 135 50 115 48.1
 pT3 or greater 135 50 124 51.9
pNa
 pN0 236 95.2 209 95.4
 pN1 or greater 12 4.8 10 4.6
Margins
 Negative 137 50.7 116 48.5
 Positive 133 49.3 123 51.5
TMPRSS2/ERGb,c
 Negative 92 34.1 105 48.8
 Positive 178 65.9 110 51.2
  1. SP, specimen; cT, clinical stage; PSA, prostatic specific antigen; pN, lymphnode pathological stage
  2. aLymphadenectomy was limited to the obturator fossa in most of the cases at the inclusion period.
  3. bValues in qRT-PCR columns refer to TMPRSS2-ERG status determined using reverse transcription polymerase chain reaction (RT-PCR), fluorescent in situ hybridization (FISH), and quantitative RTPCR (qRT-PCR); values in IHC columns refer to immunohistochemical ERG evaluation
  4. cIHC ERG expression was not detectable in 24/239 cases