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Table 1 Clinico-pathological features of the patients included in the study

From: Insulin-like growth factor 1 receptor affects the survival of primary prostate cancer patients depending on TMPRSS2-ERG status

Parameter

qRT-PCR (n = 270)

IHC (n = 239)

No. Pts

%

No. Pts

%

Age

 ≤ 55

15

5.6

12

5

 56-65

81

30

72

30.1

 66-75

138

51.1

122

51

 > 75

36

13.3

33

13.8

Gleason-sp

 2-6

109

40.4

87

36.4

 7

129

47.8

123

51.5

 Greater than 7

32

11.9

29

12.1

PSA (ng/ml)

 10 or less

155

57.6

133

55.9

 10-20

74

27.5

69

29

 Greater than 20

40

14.9

36

15.1

cT

 cT2b or less

248

92.2

219

92

 cT3a or greater

21

7.8

19

8

pT

 pT2 or less

135

50

115

48.1

 pT3 or greater

135

50

124

51.9

pNa

 pN0

236

95.2

209

95.4

 pN1 or greater

12

4.8

10

4.6

Margins

 Negative

137

50.7

116

48.5

 Positive

133

49.3

123

51.5

TMPRSS2/ERGb,c

 Negative

92

34.1

105

48.8

 Positive

178

65.9

110

51.2

  1. SP, specimen; cT, clinical stage; PSA, prostatic specific antigen; pN, lymphnode pathological stage
  2. aLymphadenectomy was limited to the obturator fossa in most of the cases at the inclusion period.
  3. bValues in qRT-PCR columns refer to TMPRSS2-ERG status determined using reverse transcription polymerase chain reaction (RT-PCR), fluorescent in situ hybridization (FISH), and quantitative RTPCR (qRT-PCR); values in IHC columns refer to immunohistochemical ERG evaluation
  4. cIHC ERG expression was not detectable in 24/239 cases