Skip to main content

Table 2 TERs measured in various MCF-7 MT3 mutants

From: The unique C- and N-terminal sequences of Metallothionein isoform 3 mediate growth inhibition and Vectorial active transport in MCF-7 cells

MCF-7 Cell Lines Average TER Day 5 (Ω/cm2) Average TER Day 6 (Ω/cm2) Average TER Day 7 (Ω/cm2) Average TER Day 5, 6 and 7 (Ω/cm2)
MT3 35.32 +/− 5.81 53.57 +/− 13.88 52.27 +/− 12.11 48.72
MT3ΔCT 41.99 +/− 9.26 53.08 +/− 9.57 47.67 +/− 5.16 47.58
MT3ΔNT 26.39 +/− 1.99 44.06 +/− 3.37 28.16 +/− 5.87 32.87
MT1E 32.68 +/− 7.26 35.92 +/− 6.98 30.91 +/− 8.41 33.17
MT1E-CT 22.96 +/− 11.94 29.34 +/− 9.40 37.98 +/− 7.07 30.09
MT1E-NT 37.58 +/− 10.23 34.3 +/− 9.4 32.28 +/− 12.61 34.72
MCF-7 (parent) 38.80 +/− 12.10 22.21 +/− 4.63 32.4 +/− 1.92 31.13
pcDNA 6.2/V5 Blank vector 41.99 +/− 5.38 27.38 +/− 10.76 36.80 +/− 6.48 35.39
  1. Average TER for each mutant cell line was measured on days 5, 6 and 7 and is expressed as Ω/cm2 +/− the SEM. The combined average TER for days 5, 6 and 7 was used to determine the relationship between TER and the presence or absence of the N- and C- terminal region of MT3. No statistical significance using the one-way ANOVA test and Dunnet’s post-test for multiple comparisons using the pcDNA 6.2/V5 cell line as control
\