Fig. 3

Top 120 DEGs between CMT-93 cells, liver metastases derived from CMT-93 and macroscopically tumour-free liver. Expression data are depicted as a data matrix in which each row represents a gene and each column represents a sample. The colour coding bar above the heat map marks the samples from the CMT-93 cell line (samples CMT93V1–3) as green, those from the liver metastases derived from CMT-93 (samples D208-210 K, D212K) in red and those of macroscopically tumour-free liver (samples D208-210 N, D212-215 N) in blue. Expression levels are depicted according to the colour scale presented in the top left corner. Red indicates expression levels above and green below the median, respectively. The magnitude of deviation from the median is represented by the colour saturation. The hierarchical clustering is visualized by the dendrogram at the top, which illustrates the degree of relatedness in gene expression