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Table 3 Univariate and multivariate analysis of overall survival (OS) and progression free survival (PFS) in relation to Residual Tumor after surgery and MAL mRNA expression. Model adjusted by age on continuous scale

From: MAL gene overexpression as a marker of high-grade serous ovarian carcinoma stem-like cells that predicts chemoresistance and poor prognosis

Variables OS PFS
  n HR 95% CI p value n HR 95% CI p value
Univariate survival analysis         
 MAL mRNA RQ (medium/high vs low tertile) 74 2.28 1.23–4.23 0.009 74 1.81 1.05–3.12 0.033
 Residual Tumor after surgery (RT > 0 cm vs RT = 0 cm) 74 5.11 1.59–16.40 0.006 74 4.25 1.81–9.94 <0.001
Multivariate survival analysis         
 MAL mRNA RQ (medium/high vs low tertile) 74 2.01 1.07–3.78 0.029 74 1.66 0.95–2.90 0.074
 Residual Tumor after surgery (RT > 0 cm vs RT = 0 cm) 74 4.32 1.34–13.96 0.014 74 3.88 1.64–9.15 0.002