Table 2 Odds ratio and p-values for the cytokines and chemokines evaluated as risk factor for gastric cancer
Cytokine | Positive (%) | Negative (%) | OR | IC 95% | p-value |
|---|---|---|---|---|---|
IL-1β | |||||
Healthy | 65 (49) | 50 (70) | |||
Gastric cancer | 68 (51) | 21 (30) | 2.49 | 1.35–4.59 | 0.003 |
IL-6 | |||||
Healthy | 4 (10) | 111 (68) | |||
Gastric cáncer | 35 (90) | 54 (32) | 17.9 | 6.08–53.19 | 0.00 |
IFN –γ | |||||
Healthy | 56 (35) | 64 (61) | |||
Gastric cancer | 101 (65) | 42 (39) | 2.75 | 1.65–4.57 | 0.00 |
IL-10 | |||||
Healthy | 21 (36) | 94 (67) | |||
Gastric cancer | 43 (64) | 46 (33) | 4.18 | 2.23–7.85 | 0.00 |
MCP-1 | |||||
Healthy | 59 (60) | 56 (50) | |||
Gastric cancer | 38 (40) | 53 (50) | 0.68 | 0.39–1.19 | 0.21 |
IL-8 | |||||
Healthy | 49 (40) | 71 (50) | |||
Gastric cancer | 71 (60) | 71 (50) | 1.45 | 0.89–2.37 | 0.17 |
TNF-α | |||||
Healthy | 82 (57) | 33 (58) | |||
Gastric cancer | 63 (43) | 28 (42) | 0.91 | 0.49–1.65 | 0.76 |
TGF-β | |||||
Healthy | 64 (52) | 56 (40) | |||
Gastric cancer | 58 (48) | 83 (60) | 0.61 | 0.37–0.99 | 0.06 |