|
Risk of vascular invasion
|
|
Age (>50 years vs < =50 years)
|
0.68
|
0.44–1.04
|
0.078
|
|
Alpha-fetoprotein (> 20 ng/ml vs < = 20 ng/ml)
|
2.51
|
1.59–3.96
|
<0.01*
|
|
Tumor number (Multiple vs Single)
|
2.18
|
1.04–4.55
|
0.038*
|
|
Diameter (> 3 cm vs < = 3 cm)
|
1.73
|
1.04–2.88
|
0.035*
|
|
Edmonson grading (Grades III/IV vs Grades I/II)
|
2.48
|
1.21–5.05
|
0.013*
|
|
Tumor capsule (Incomplete/absent vs Complete)
|
2.17
|
1.25–3.77
|
0.006*
|
|
Seral HBeAg (Positive vs Negative)
|
1.83
|
1.10–3.03
|
0.019*
|
|
Seral HBV DNA load (> 50 IU/ml vs < = 50 IU/ml)
|
1.68
|
1.06–2.65
|
0.027*
|
|
Risk of microscopic vascular invasion
|
|
Alpha-fetoprotein (> 20 ng/ml vs < = 20 ng/ml)
|
2.59
|
1.65–4.05
|
<0.01*
|
|
Tumor number (Multiple vs Single)
|
2.21
|
1.09–4.51
|
0.028*
|
|
Diameter (> 3 cm vs < = 3 cm)
|
1.58
|
0.96–2.61
|
0.074
|
|
Edmonson grading (Grades III/IV vs Grades I/II)
|
2.24
|
1.11–4.54
|
0.024*
|
|
Tumor capsule (Incomplete/absent vs Complete)
|
2.04
|
1.18–3.51
|
0.011*
|
|
Seral HBeAg (Positive vs Negative)
|
1.59
|
0.98–2.57
|
0.059
|
|
Seral HBV DNA load (> 50 IU/ml vs < = 50 IU/ml)
|
1.76
|
1.12–2.76
|
0.013*
|
|
Risk of portal vein tumor thrombus
|
|
DCP (>100 mAU/ml vs < = 100 mAU/ml)
|
2.90
|
1.17–7.12
|
0.022*
|
|
Tumor diameter (>3 cm vs < =3 cm)
|
8.86
|
2.67–29.39
|
<0.01*
|
|
Tumor capsule (Incomplete/absence vs Complete)
|
3.59
|
1.56–8.25
|
0.003*
|
|
Seral HBeAg (Positive vs Negative)
|
1.67
|
1.01–2.75
|
0.046*
|
|
Anti-virus treatment (Yes vs No)
|
0.59
|
0.33–1.05
|
0.075
|
