|  | Unadjusted estimates, mean (SD) | Adjusted analysis for intervention vs usual carea | |||
---|---|---|---|---|---|---|
Intervention group | Control group | Intervention group | Control group | P value1) | ||
MET/h/day | Baseline | 26.7 (27.5) | 27.5 (19.8) | Â | Â | Â |
3 months | 27.1 (25.4) | 24.3 (24.6) | 26.2 (2.2) | 23.9 (3.0) | 0.540 | |
12 months | 23.5 (23.6) | 22.9 (24.6) | 22.9 (2.3) | 22.8 (3.3) | 0.975 | |
PTGI-Total | Baseline | 63.1 (18.5) | 61.8 (18.9) | Â | Â | Â |
3 months | 63.6 (19.3) | 61.2 (18.6) | 62.7 (1.3) | 62.1 (1.7) | 0.791 | |
12 months | 66.6 (19.3) | 60.2 (19.1) | 66.3 (1.6) | 61.2 (2.2) | 0.065* | |
Vegetable intake n(%), ≥5 serves/day | Baseline | 45 (33.6) | 22 (30.6) |  |  |  |
3 months | 52 (42.6) | 27 (40.9) | 33.6 (4.9) | 31.0 (6.3) | 0.819 | |
12 months | 41 (36.9) | 26 (42.6) | 31.0 (5.4) | 37.3 (6.7) | 0.413 | |
Leadership | Baseline | 121.3 (21.2) | 120.1 (20.8) | Â | Â | Â |
3 months | 125.0 (21.7) | 121.6 (20.2) | 123.1 (1.3) | 121.8 (1.9) | 0.552 | |
12 months | 127.7 (22.1) | 122.8 (20.6) | 125.4 (1.6) | 123.3 (2.2) | 0.433 | |
HADS | ||||||
 Anxiety | Baseline | 5.7 (3.4) | 5.9 (3.1) |  |  |  |
3 months | 5.0 (3.0) | 6.1 (3.1) | 5.2 (0.2) | 6.0 (0.3) | 0.025** | |
12 months | 5.1 (3.0) | 5.8 (2.9) | 5.2 (0.3) | 5.7 (0.4) | 0.228 | |
 Depression | Baseline | 6.4 (3.5) | 6.1 (3.1) |  |  |  |
3 months | 5.5 (3.3) | 5.4 (2.8) | 5.6 (0.2) | 5.6 (0.3) | 0.986 | |
12 months | 5.4 (3.4) | 5.6 (3.1) | 5.3 (0.3) | 5.7 (0.4) | 0.428 | |
EORTC QLQ-C30 | ||||||
 Functional scales | ||||||
  Global health status | Baseline | 64.5 (19.9) | 63.4 (18.7) |  |  |  |
3 months | 67.7 (18.7) | 65.7 (17.5) | 67.0 (1.6) | 66.0 (2.3) | 0.705 | |
12 months | 70.1 (17.1) | 65.3 (17.9) | 69.0 (1.6) | 66.0 (2.2) | 0.269 | |
  Physical functioning | Baseline | 78.6 (13.5) | 77.9 (11.1) |  |  |  |
3 months | 80.0 (12.1) | 78.4 (12.0) | 79.4 (0.9) | 79.3 (1.3) | 0.942 | |
12 months | 82.9 (13.1) | 78.2 (12.4) | 81.9 (1.2) | 78.7 (1.6) | 0.123 | |
  Role functioning | Baseline | 79.4 (21.4) | 77.9 (19.8) |  |  |  |
3 months | 80.9 (18.1) | 77.3 (18.4) | 80.3 (1.5) | 78.5 (2.2) | 0.497 | |
12 months | 82.7 (19.8) | 79.9 (18.9) | 80.9 (1.8) | 81.1 (2.4) | 0.958 | |
  Emotional functioning | Baseline | 76.8 (19.4) | 73.0 (23.0) |  |  |  |
3 months | 78.0 (19.1) | 74.5 (16.5) | 76.7 (1.5) | 75.3 (2.2) | 0.602 | |
12 months | 78.0 (19.9) | 75.9 (18.3) | 76.2 (1.9) | 77.7 (2.4) | 0.625 | |
  Cognitive functioning | Baseline | 76.7 (19.9) | 72.6 (20.9) |  |  |  |
3 months | 80.1 (17.2) | 72.5 (20.2) | 77.6 (1.4) | 75.1 (2.4) | 0.322 | |
12 months | 78.1 (14.9) | 76.5 (19.2) | 76.8 (1.6) | 78.4 (2.1) | 0.552 | |
  Social functioning | Baseline | 75.8 (26.8) | 73.1 (23.4) |  |  |  |
3 months | 85.4 (19.3) | 76.3 (20.2) | 84.8 (1.8) | 77.4 (2.5) | 0.018 | |
12 months | 85.3 (19.5) | 78.2 (22.4) | 84.8 (2.2) | 79.0 (2.9) | 0.123 | |
 Symptom scales | ||||||
  Fatigue | Baseline | 38.6 (20.9) | 40.8 (21.6) |  |  |  |
3 months | 33.5 (17.8) | 38.1 (17.7) | 34.3 (1.5) | 37.6 (2.2) | 0.214 | |
12 months | 33.8 (16.1) | 42.4 (21.4) | 34.8 (1.6) | 41.9 (2.1) | 0.010** | |
  Nausea/vomiting | Baseline | 4.6 (10.0) | 4.2 (10.6) |  |  |  |
3 months | 5.7 (10.6) | 5.3 (9.8) | 5.6 (0.9) | 6.2 (1.3) | 0.733 | |
12 months | 6.4 (14.5) | 7.8 (15.3) | 6.5 (1.6) | 7.7 (2.1) | 0.660 | |
  Pain | Baseline | 15.4 (19.2) | 21.4 (19.0) |  |  |  |
3 months | 11.9 (16.0) | 19.6 (19.6) | 13.6 (1.5) | 17.4 (2.1) | 0.146 | |
12 months | 13.1 (17.6) | 19.7 (21.4) | 15.5 (1.8) | 16.2 (2.3) | 0.810 | |
  Dyspnea | Baseline | 11.9 (19.9) | 19.4 (21.0) |  |  |  |
3 months | 8.2 (15.9) | 13.7 (16.6) | 10.3 (1.3) | 11.3 (1.9) | 0.668 | |
12 months | 10.6 (19.5) | 13.6 (17.9) | 12.1 (2.0) | 11.3 (2.6) | 0.797 | |
  Insomnia | Baseline | 28.8 (30.0) | 30.3 (28.9) |  |  |  |
3 months | 24.1 (24.50 | 26.7 (26.9) | 25.0 (2.1) | 25.7 (3.1) | 0.850 | |
12 months | 26.2 (27.9) | 32.0 (27.2) | 27.6 (2.5) | 29.1 (3.4) | 0.732 | |
  Appetite loss | Baseline | 12.8 (20.9) | 15.4 (24.8) |  |  |  |
3 months | 10.7 (17.6) | 17.3 (23.6) | 11.3 (1.8) | 17.7 (2.6) | 0.048 | |
12 months | 11.6 (17.6) | 13.6 (20.3) | 12.1 (2.0) | 13.7 (2.6) | 0.631 | |
  Constipation | Baseline | 16.9 (26.7) | 18.9 (24.1) |  |  |  |
3 months | 14.7 (23.3) | 16.3 (21.6) | 16.5 (1.8) | 16.0 (2.7) | 0.882 | |
12 months | 12.6 (18.1) | 17.7 (20.5) | 19.5 (2.2) | 16.5 (2.9) | 0.414 | |
  Diarrhea | Baseline | 13.8 (20.7) | 11.4 (18.8) |  |  |  |
3 months | 12.6 (18.1) | 14.0 (17.9) | 19.8 (4.1) | 10.0 (5.4) | 0.151 | |
12 months | 20.5 (45.6) | 9.5 (20.4) | 11.9 (1.5) | 15.3 (2.2) | 0.211 | |
  Financial Difficulties | Baseline | 20.3 (28.6) | 23.4 (26.0) |  |  |  |
3 months | 15.5 (25.5) | 26.8 (37.1) | 17.4 (2.6) | 27.0 (3.7) | 0.036 ** | |
12 months | 18.9 (26.6) | 20.4 (27.9) | 18.9 (2.5) | 19.3 (3.3) | 0.920 | |
  The MOS-SSS | Baseline | 65.6 (20.9) | 65.6 (20.6) |  |  |  |
3 months | 66.3 (21.1) | 67.9 (19.3) | 66.9 (1.4) | 65.7 (2.0) | 0.621 | |
12 months | 66.6 (21.1) | 68.0 (19.7) | 67.1 (1.7) | 65.3 (2.4) | 0.535 | |
  Health Behavior | Baseline | 4.9 (3.1) | 5.2 (2.7) |  |  |  |
3 months | 6.4 (2.7) | 5.5 (3.0) | 6.9 (0.3) | 6.2 (0.4) | 0.147 | |
12 months | 7.0 (2.8) | 6.3 (2.7) | 6.3 (0.2) | 5.3 (0.3) | 0.015** | |
  IES-R | Baseline | 2.3 (0.8) | 2.5 (0.7) |  |  |  |
3 months | 2.2 (0.7) | 2.2 (0.7) | 2.3 (0.1) | 2.2 (0.1) | 0.759 | |
12 months | 2.1 (0.7) | 2.3 (0.8) | 2.1 (0.1) | 2.3 (0.1) | 0.068 * |