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Table 2 Distribution of baseline characteristics by age groupa

From: Systemic therapy in younger and elderly patients with advanced biliary cancer: sub-analysis of ABC-02 and twelve other prospective trials

  Covariate <40 years
Total N = 36
N (%)
≥40 years
Total N = 1127
N (%)
P-valueb <70 years
Total N = 903
N (%)
≥70 years
Total N = 260
N (%)
P-valueb
Gender Female 16 (44) 597 (53) 0.31 482 (53) 131 (50) 0.39
Male 20 (56) 530 (47)   421 (47) 129 (50)
ECOG performance status 0 10 (28) 350 (31) 0.59 285 (32) 75 (29) 0.24
1 16 (44) 572 (51)   455 (50) 133 (51)
2 4 (11) 81 (7)   60 (7) 25 (10)
Not available 6 (17) 124 (11)   103 (11) 27 (10)
Disease Stage Locally advanced 9 (25) 295 (26) 0.80 233 (26) 71 (27) 0.43
Metastatic 27 (75) 800 (71)   652 (72) 175 (67)
Not available 0 (0) 32 (3)   18 (2) 14 (5)
Treatment Combination 23 (64) 809 (72) 0.20 650 (72) 182 (70) 0.48
Monotherapy 12 (33) 301 (27)   239 (26) 74 (28)
Not available 1 (3) 17 (2)   14 (2) 4 (2)
  1. ECOG performance status: Eastern Cooperative Oncology Group Performance Status
  2. aDue to rounding, all percentages in Table 2 may not equal 100%. bChi-squared test; performed excluding the category “not available”