Table 2 Distribution of baseline characteristics by age groupa
Covariate | <40 years Total N = 36 N (%) | ≥40 years Total N = 1127 N (%) | P-valueb | <70 years Total N = 903 N (%) | ≥70 years Total N = 260 N (%) | P-valueb | |
|---|---|---|---|---|---|---|---|
Gender | Female | 16 (44) | 597 (53) | 0.31 | 482 (53) | 131 (50) | 0.39 |
Male | 20 (56) | 530 (47) | 421 (47) | 129 (50) | |||
ECOG performance status | 0 | 10 (28) | 350 (31) | 0.59 | 285 (32) | 75 (29) | 0.24 |
1 | 16 (44) | 572 (51) | 455 (50) | 133 (51) | |||
2 | 4 (11) | 81 (7) | 60 (7) | 25 (10) | |||
Not available | 6 (17) | 124 (11) | 103 (11) | 27 (10) | |||
Disease Stage | Locally advanced | 9 (25) | 295 (26) | 0.80 | 233 (26) | 71 (27) | 0.43 |
Metastatic | 27 (75) | 800 (71) | 652 (72) | 175 (67) | |||
Not available | 0 (0) | 32 (3) | 18 (2) | 14 (5) | |||
Treatment | Combination | 23 (64) | 809 (72) | 0.20 | 650 (72) | 182 (70) | 0.48 |
Monotherapy | 12 (33) | 301 (27) | 239 (26) | 74 (28) | |||
Not available | 1 (3) | 17 (2) | 14 (2) | 4 (2) |