Trial-reported test characteristics | Test characteristic based on literature | Costs (Euros) | |||||
---|---|---|---|---|---|---|---|
Sensitivity [95% CI] | Specificity [95% CI] | Positive predictive value [95% CI] | Negative predictive value [95% CI] | Sensitivity | Specificity | ||
EUA | 60 [14.7–94.7] | 100 [91.4–100.0] | 100.0 [29.2–100.0] | 95.3 [84.2–99.4] | * | * | 468 |
PET-CT | 75 [19.4–99.4] | 83 [67.9–92.8] | 30.0 [6.7–65.2] | 97.1 [85.1–99.9] | 79.9a | 87.5a | 1067 |
DW-MRI | 60 [14.7–94.7] | 95 [83.5–99.4] | 60.0 [14.7–94.7] | 95.1 [83.5–99.4] | 89.0b | 86.0b | 246 |
Combined PET-CT and DW-MRI | 100 [39.8–100.0] | 93 [80.1–98.5] | 57.1 [18.4–90.1] | 100.0 [90.7–100.0] | * | * | 1313 |