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Table 2 Differential Pathway Enrichment in FF samples

From: Comparison of triple-negative breast cancer molecular subtyping using RNA from matched fresh-frozen versus formalin-fixed paraffin-embedded tissue

Gene Set Name # Genes Overlap p-value FDR q-value
Cellular Compartment C5
Cytoplasm 391 1.77E-128 4.13E-126
Cytoplasmic part 265 8.87E-90 1.03E-87
Organelle part 228 2.04E-76 1.59E-74
Intracellular organelle part 227 4.69E-76 2.73E-74
Nucleus 243 3.58E-71 1.67E-69
Macromolecular complex 193 9.82E-70 3.81E-68
Mitochondrion 101 3.55E-52 1.18E-50
Protein complex 150 3.96E-48 1.15E-46
Membrane 240 1.92E-42 4.97E-41
Mitochondrial part 55 4.45E-36 1.04E-34
Canonical Pathways C2
Huntingtons disease 71 7.32E-46 6.52E-43
TCA cycle and electron transport 63 9.81E-46 6.52E-43
Alzheimers disease 67 1.96E-44 6.53E-42
Adaptive immune system 116 1.96E-44 6.53E-42
Immune system 155 5.67E-44 1.51E-41
Oxidative phosphorylation 60 1.88E-43 4.17E-41
Parkinsons disease 59 1.08E-42 2.06E-40
Metabolism of proteins 111 2.29E-42 3.81E-40
Respiratory electron transport 50 3.40E-40 5.02E-38
Metabolism of RAN 83 2.13E-37 2.83E-35