Table 1 Descriptive characteristics by breast cancer severity, including women from the AMORIS database 1989–2011
Any BC(N = 1824) | All BC w/severity (N = 1411) | Good (N = 900) | Moderate (N = 327) | Severe (N = 184) | |
|---|---|---|---|---|---|
N (%) | N(%) | N(%) | N(%) | N(%) | |
Age at Baseline (years) | |||||
≤ 49 | 810 (44.41) | 632 (44.79) | 405 (45.00) | 133 (40.67) | 94 (51.09) |
50–59 | 572 (31.36) | 459 (32.43) | 310 (34.44) | 93 (28.44) | 56 (30.43) |
60–69 | 308 (16.89) | 235 (16.65) | 140 (15.56) | 69 (21.10) | 26 (14.13) |
≥ 70 | 134 (7.35) | 85 (6.02) | 45 (5.00) | 32 (9.79) | 8 (4.35) |
Mean Interval (years) | |||||
Time from baseline to BC (SD) | 11.56 (6.46) | 11.70 (6.52) | 11.71 (6.42) | 12.67 (6.85) | 9.91 (6.06) |
Parity | |||||
Yes | 1389 (76.15) | 1072 (75.97) | 682 (75.78) | 246 (75.23) | 144 (78.26) |
No | 435 (23.85) | 339 (24.03) | 218 (24.22) | 81 (24.77) | 40 (21.74) |
Socioeconomic Status | |||||
High | 747 (40.95) | 594 (42.10) | 397 (44.11) | 128 (39.14) | 69 (37.50) |
Low | 895 (49.07) | 689 (48.83) | 432 (48.00) | 160 (48.93) | 97 (52.72) |
Unclassified/Missing | 182 (9,98) | 128 (9.07) | 71 (7.89) | 39 (11.93) | 18 (9.78) |
Fasting Status | |||||
Fasting | 1186 (65.02) | 888 (62.93) | 557 (61.89) | 216 (66.06) | 115 (62.50) |
Non-fasting | 256 (14.04) | 204 (14.46) | 121 (13.44) | 43 (13.15) | 40 (21.74) |
Unknown | 382 (20.94) | 319 (22.61) | 222 (24.67) | 68 (20.80) | 29 (15.76) |
Tumour Side | |||||
Left | 759 (50.63) | 701 (49.68) | 440 (48.49) | 168 (47.56) | 93 (50.54) |
Right | 740 (49.37) | 674 (47.77) | 428 (47.56) | 159 (48.62) | 87 (47.28) |
Missing | 325 (17.82) | 36 (2.55) | 32 (3.56) | 0 (0.00) | 4 (11.11) |
Invasive Gradea | |||||
Grade 1 | 124 (6.80) | 113 (8.01) | 98 (10.89) | 14 (4.28) | 1 (0.54) |
Grade 2 | 296 (16.23) | 280 (19.84) | 178 (19.78) | 93 (28.44) | 9 (4.89) |
Grade 3 | 170 (9.32) | 161 (11.41) | 70 (7.78) | 56 (17.13) | 35 (19.02) |
Missing | 1234 (67.65) | 857 (60.74) | 544 (61.56) | 164 (50.15) | 139 (75.54) |
T-Stage | |||||
T0: no evidence of primary tumour | 23 (1.26) | 21 (1.49) | 17 (1.89) | 1 (0.31) | 3 (1.62) |
T1: ≤ 2 cm | 1018 (55.81) | 966 (68.46) | 883 (98.11) | 56 (17.13) | 27 (14.67) |
T2: 2-5 cm | 471 (25.82) | 365 (25.87) | 0 (0.00) | 256 (78.29) | 109 (59.24) |
T3: > 5 cm | 36 (1.97) | 21 (1.49) | 0 (0.00) | 14 (4.28) | 7 (3.80) |
T4: tumour of any size with extension to the chest wall and/or skin | 41 (2.25) | 21 (1.49) | 0 (0.00) | 0 (0.00) | 38 (20.65) |
TX: primary tumour cannot be assessed | 235 (12.88) | 38 (2.69) | 0 (0.00) | 0 (0.00) | 0 (0.00) |
N-Stage | |||||
N0: negative | 1332 (73.03) | 1233 (87.38) | 900 (100.00) | 227 (69.42) | 106 (57.61) |
N1: 1–3 | 226 (12.39) | 167 (11.84) | 0 (0.00) | 100 (30.58) | 67 (36.41) |
N2: 4–9 | 8 (0.44) | 5 (0.35) | 0 (0.00) | 0 (0.00) | 5 (2.72) |
N3: ≥ 19 | 7 (0.38) | 6 (0.43) | 0 (0.00) | 0 (0.00) | 6 (3.26) |
Nx: nodes cannot be assessed | 251 (13.76) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) |
M-Stage | |||||
M0: no distant spread | 1508 (82.68) | 1390 (98.51) | 900 (100.00) | 327 (100.00) | 163 (88.59) |
M1: spread to distant organs | 22 (1.21) | 21 (1.49) | 0 (0.00) | 0 (0.00) | 21 (11.41) |
Mx: presence of metastasis cannot be assessed | 294 (16.12) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) |
Oestrogen Receptor Status | |||||
Positive | 1013 (55.54) | 974 (69.03) | 626 (69.56) | 327 (100.00) | 21 (11.41) |
Negative | 220 (12.06) | 213 (15.10) | 87 (9.67) | 0 (0.00) | 126 (68.48) |
Missing | 591 (32.40) | 224 (15.88) | 187 (20.78) | 0 (0.00) | 37 (20.11) |
Progesterone Receptor Status | |||||
Positive | 839 (46.00) | 811 (57.48) | 531 (59.00) | 246 (75.23) | 34 (18.48) |
Negative | 379 (20.78) | 361 (25.58) | 172 (19.11) | 77 (23.55) | 112 (60.87) |
Missing | 606 (33.22) | 239 (16.94) | 197 (21.89) | 4 (1.22) | 38 (20.65) |
HER2-status | |||||
Positive | 38 (2.08) | 32 (2.27) | 13 (1.44) | 13 (3.98) | 6 (3.26) |
Negative | 289 (15.84) | 264 (18.71) | 172 (19.11) | 71 (21.71) | 21 (11.41) |
Missing | 1497 (82.07) | 1115 (79.02) | 715 (79.44) | 243 (74.31) | 157 (85.33) |
CCI | |||||
0 | 1681 (92.16) | 1306 (92.56) | 834 (92.67) | 302 (92.35) | 170 (92.39) |
1 | 70 (3.84) | 54 (3.83) | 32 (3.56) | 14 (4.28) | 8 (4.35) |
2 | 54 (2.96) | 35 (2.48) | 24 (2.67) | 8 (2.45) | 3 (1.63) |
3+ | 19 (1.04) | 16 (1.13) | 10 (1.11) | 3 (0.92) | 3 (1.63) |
Dead | |||||
BC-Death | 245 (13.43) | 371 (26.29) | 56 (6.22) | 48 (14.68) | 60 (32.61) |