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Table 2 Associations between ABCG2 expression and clinical parameters in patients with clear cell RCC

From: ABCG2 is a potential prognostic marker of overall survival in patients with clear cell renal cell carcinoma

Parameters Value ABCG2(−) ABCG2(+) ABCG2(++) P
Gender Female 16 (28%) 17 (33%) 4 (36%) 0.510
  Male 41 (72%) 35 (67%) 7 (64%)  
Age at surgery (years) <60 4172%) 33 (63%) 4 (36%) 0.054
  ≥60 16 (28%) 19 (37%) 7 (64%)  
Symptoms on first diagnosis Negative 36 (63%) 33 (63%) 4 (36%) 0.351
  Positive 21 (37%) 19 (37%) 7 (64%)  
pT T1a 23 (40%) 13 (25%) 1 (9%) 0.180
  T1b 22 (39%) 28 (54%) 5 (45%)  
  T2 9 (16%) 6 (12%) 3 (27%)  
  T3 3 (5%) 5 (10%) 2 (18%)  
Regional lymph node metastasis Negative 56 (98%) 51 (98%) 9 (82%) 0.103
  Positive 1 (2%) 1 (2%) 2 (18%)  
Distant metastasis on first diagnosis Negative 54 (95%) 40 (77%) 7 (64%) 0.001*
  Positive 3 (5%) 12 (23%) 4 (36%)  
Fuhrman grade 1 14 (25%) 4 (8%) 0 (0%) 0.014*
  2 31 (54%) 35 (67%) 4 (36%)  
  3 9 (16%) 11 (21%) 5 (45%)  
  4 3 (5%) 2 (4%) 2 (18%)  
Five-year survival Alive 53 (93%) 40 (77%) 3 (27%) <0.001*
  Deceased 4 (7%) 12 (23%) 8 (73%)  
Surgery type Radical Nephrectomy 2 (4%) 4 (8%) 0 (0%) 0.441
  Partial Nephrectomy 55 (96%) 48 (92%) 11 (100%)