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Fig. 5 | BMC Cancer

Fig. 5

From: Congenic rats with higher arylamine N-acetyltransferase 2 activity exhibit greater carcinogen-induced mammary tumor susceptibility independent of carcinogen metabolism

Fig. 5

Rat NAT2 PABA acetylation and folate-dependent AcCoA hydrolysis activity. a, c PABA acetylation activity. b, d Folate-dependent AcCoA hydrolytic activity. a, b Triplicates from the same recombinant lysates. c, d Lysates of individual tissues collected from 5 rapid (closed bars) or 5 slow (open bars) acetylator NAT2 F344 congenic rats. “ND” = not detectable. Differences between rapid and slow acetylator rats differed significantly ***p < 0.001; **p < 0.01

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