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Fig. 2 | BMC Cancer

Fig. 2

From: Congenic rats with higher arylamine N-acetyltransferase 2 activity exhibit greater carcinogen-induced mammary tumor susceptibility independent of carcinogen metabolism

Fig. 2

Weekly body mass (mean grams ± SEM) of rapid and slow acetylator Nat2 congenic rats post administration of specified carcinogen or vehicle control. In all three panels squares represent rapid acetylator and circles represent slow acetylator congenic rats. Filled-shapes represent vehicle-treated and unfilled-shapes represent. MNU or DMBA-treated. a Weights for rats treated with MNU at 3 weeks of age. The difference between weights of the vehicle-treated and MNU-treated is statistically significant by two-way ANOVA with Bonferroni post hoc test (p < 0.05). b Weights for rats treated with MNU at 8 weeks of age. The weights of the vehicle-treated and MNU treated rats were statistically significant by two-way ANOVA with Bonferroni post hoc test (p < 0.05). c Weights for rats administrated DMBA at 8 weeks of age. The weights of the vehicle-treated and DMBA-treated rats were not statistically significant by two-way ANOVA with Bonferroni post hoc test (p > 0.05). In all panels, weights of MNU/DMBA-treated rats were not significantly different between rapid and slow NAT2 acetylator rat strains

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BMC Cancer

ISSN: 1471-2407

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