Fig. 7

LncRNA XIST regulates HCC via miR-181a. a and b The regulation of XIST on PTEN was mediated by miR-181a. * vs Blank, p < 0.05. ** vs Blank, p < 0.01. ^## vs miR-181a mimics or miR-181a inhibitor group, p < 0.01. c and d The regulation of XIST on HCC proliferation was mediated by miR-181a. ** vs si-XIST or pcDNA-XIST group, p < 0.01. ^## vs miR-181a mimics or miR-181a inhibitor group, p < 0.01. e and f XIST inhibited the migration and invasion of HCCLM3 cells, while the transfection of miR-181a mimics abolished the inhibition. lncRNA, long non-coding RNA; HCC, hepatocellular carcinoma. ^## vs si-XIST or pcDNA-XIST group, p < 0.01