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Fig. 4 | BMC Cancer

Fig. 4

From: Long non-coding RNA XIST regulates PTEN expression by sponging miR-181a and promotes hepatocellular carcinoma progression

Fig. 4

MiR-181a promoted HCC cell invasion and EMT by activating AKT signaling. a The protein expression of EMT related genes (Snail, Slug, N-cadherin, Vimentin and E-cadherin), MMP-2, and MMP-9. b Western blot analysis of phosphorylated (active) AKT and mTOR in HCC cells transfected with miR-181a mimics or inhibitor. HCC, hepatocellular carcinoma. EMT, epithelial-to-mesenchymal transition. All values are mean ± SD. ** vs NC group, p < 0.01

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BMC Cancer

ISSN: 1471-2407

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