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Table 1 The main characteristics of the included studies

From: Prognostic value of transforming growth factor-beta in patients with colorectal cancer who undergo surgery: a meta-analysis

Author Year of publication Country Time Sample size Males Mean of age (range) Patients Stage (UICC) Differentiation Surgery Chemo−/Radio-therapy Follow-up time (median, months)
Zhu J 2015 China 2003–2009 115 70 62 (29, 89) CRC All All All NR/NR NR
Chun HK 2014 Korea 2006–2007 201 132 58.6 Rectal cancer III All All Partial/Partial 57.8
Langenskiöld M 2013 Sweden 1999–2003 136 78 75 (44, 91) CRC I-III All All Partial/No 51.0
Uhlmann ME 2012 Germany 1998–2001 103 67 66.7 CRC All NR All NR/NR 104.5
Lampropoulos P 2012 Greece 2005–2006 195 103 68.6 (36, 90) CRC All NR All No/No 56.0
Li X 2011 China 2003–2004 147 86 NR (24, 87) Colon cancer All (Duke’s stage) NR All Partial/No ≥ 60.0
Khanh do T 2011 Japan 1998–2005 206 114 63.3 (19, 92) CRC All All All Partial/NR ≥ 60.0
Wincewicz A 2010 Poland 2004–2008 72 35 NR CRC All Moderate and poor All NR/NR NR
Gulubova M 2010 Bulgaria 1997–2006 142 92 65 b (39, 96) CRC All All All NR/NR 37.6
Bellone G 2010 Italy 2004–2008 75 47 NR (24, 87) Colon cancera All (Duke’s stage) NR All NR/NR 44.0
Tsamandas AC 2004 Greece 1990–1998 124 79 66 b (25, 82) CRC All All All Partial/Partial 68.0
Robson H 1996 UK NR 72 47 70 (32, 92) CRC All All All NR/NR ≥ 36.0
Friedman E 1995 US 1994 34 18 64.6 CRC NR NR All NR/NR 57.3 (mean)
  1. CRC Colorectal cancer, NR not reported
  2. aOnly included adenoma and adenocarcinoma of the colon
  3. bMedian of age