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Table 1 The main characteristics of the included studies

From: Prognostic value of transforming growth factor-beta in patients with colorectal cancer who undergo surgery: a meta-analysis

Author

Year of publication

Country

Time

Sample size

Males

Mean of age (range)

Patients

Stage (UICC)

Differentiation

Surgery

Chemo−/Radio-therapy

Follow-up time (median, months)

Zhu J

2015

China

2003–2009

115

70

62 (29, 89)

CRC

All

All

All

NR/NR

NR

Chun HK

2014

Korea

2006–2007

201

132

58.6

Rectal cancer

III

All

All

Partial/Partial

57.8

Langenskiöld M

2013

Sweden

1999–2003

136

78

75 (44, 91)

CRC

I-III

All

All

Partial/No

51.0

Uhlmann ME

2012

Germany

1998–2001

103

67

66.7

CRC

All

NR

All

NR/NR

104.5

Lampropoulos P

2012

Greece

2005–2006

195

103

68.6 (36, 90)

CRC

All

NR

All

No/No

56.0

Li X

2011

China

2003–2004

147

86

NR (24, 87)

Colon cancer

All (Duke’s stage)

NR

All

Partial/No

≥ 60.0

Khanh do T

2011

Japan

1998–2005

206

114

63.3 (19, 92)

CRC

All

All

All

Partial/NR

≥ 60.0

Wincewicz A

2010

Poland

2004–2008

72

35

NR

CRC

All

Moderate and poor

All

NR/NR

NR

Gulubova M

2010

Bulgaria

1997–2006

142

92

65 b (39, 96)

CRC

All

All

All

NR/NR

37.6

Bellone G

2010

Italy

2004–2008

75

47

NR (24, 87)

Colon cancera

All (Duke’s stage)

NR

All

NR/NR

44.0

Tsamandas AC

2004

Greece

1990–1998

124

79

66 b (25, 82)

CRC

All

All

All

Partial/Partial

68.0

Robson H

1996

UK

NR

72

47

70 (32, 92)

CRC

All

All

All

NR/NR

≥ 36.0

Friedman E

1995

US

1994

34

18

64.6

CRC

NR

NR

All

NR/NR

57.3 (mean)

  1. CRC Colorectal cancer, NR not reported
  2. aOnly included adenoma and adenocarcinoma of the colon
  3. bMedian of age