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Table 3 Data of three EM clusters found in pooled data of 1169 breast cancer patients

From: Distribution of Ki-67 values within HER2 & ER/PgR expression variants of ductal breast cancers as a potential link between IHC features and breast cancer biology

Breast cancer

patients

Three EM clusters from the pooled patients’ data

Values for all patients

LMA (low mitotic activity)

IMA (intermediate mitotic activity)

HMA (high mitotic activity)

Mean Ki-67%

13.17

40.45

77.79

25.45

St.dev. of Ki-67

8.43

13.77

8.45

21.08

Breast cancer types

n

%

n

%

n

%

Total

%

Luminal A/B1

560

80.92

124

17.92

8

1.16

692

100.00

Luminal B2

126

63.64

68

34.34

4

2.02

198

100.00

triple-negative

41

26.62

58

37.66

55

35.71

154

100.00

pure HER2

42

33.60

73

58.40

10

8.00

125

100.00

Total

769

65.78

323

27.63

77

6.59

1169

100.00

  1. These are the results of the second stage of EM clustering that identified the three overall clusters of Ki-67 values (LMA - low mitotic activity; IMA - intermediate mitotic activity; HMA - high mitotic activity). These are the results of the second stage of EM clustering