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Table 2 Mean number of significantly altered base-pairs either specific or total (specific + shared) for CD133+ and CD133−/EpCAM+ cell fractions isolated from intraoperative colon cancer biopsies

From: DNA alterations in Cd133+ and Cd133- tumour cells enriched from intra-operative human colon tumour biopsies

 

Specific alterations

Total alterations

(N° arrays)

CNV

CD133 (20)

CNV

EpCAM (20)

T-test

p value

CNV

CD133 (20)

CNV

EpCAM (20)

T-test

p value

CNV (Mbp/patient)

28.5 ± 13.6

24.8 ± 5.1

0.801

71.7 ± 22.2

68.6 ± 22.0

0.922

% of all

53

47

 

51

49

 

Amp (Mbp/patient)

12.3 ± 11.2

2.5 ± 1.5

0.392

14.7 ± 11.5

4.63 ± 1.52

0.391

Amp % of all

83

17

 

76

24

 

Del (Mbp/patient)

16.2 ± 5.8

22.3 ± 5.0

0.433

57.1 ± 19.4

64.0 ± 22.2

0.815

Del % of all

42

58

 

47

53

 
  1. mean ± SEM, CD133 = CD133+, EpCAM = CD133/EpCAM+