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Table 5 Genetic analysis for the two groups

From: Characteristics of early-onset hematotoxicity of sunitinib in Japanese patients with renal cell carcinoma

Genotypes

 

Dose-reduced group

Dose-maintained group

Univariate analysis

  

n = 25

n = 11

p value

ABCG2 421 C/A, n (%)

Wild-type allele

12 (67)

6 (33)

1.00

 

Variant allele

13 (72)

5 (28)

 

FLT3 738 T/C, n (%)

Wild-type allele

11 (55)

9 (45)

0.04

 

Variant allele

14 (88)

2 (12)