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Table 1 Characteristics of GC patients who donated xenografts for the PDX models

From: Establishment of patient-derived gastric cancer xenografts: a useful tool for preclinical evaluation of targeted therapies involving alterations in HER-2, MET and FGFR2 signaling pathways

Characteristics

No. of patients (%)

Success rate(≥3 generation)

a P value

Gender

  

0.655

 Male

24(75.0%)

6(25%)

 

 Female

8(25.0%)

3(37.5%)

 

Age (years)

0.427

 ≥60

19(59.4%)

4(26.3%)

 

 <60

13(40.6%)

5(30.7%)

 

Stage

0.648

 I/II

6(18.8%)

1(16.7%)

 

 III/IV

26(81.2%)

8(30.8%)

 

Differentiation

0.531

 Moderate

8(25.0%)

2(25.0%)

 

 Moderate-poor

9(28.1%)

4(44.4%)

 

 Poor and undiff

15(46.9%)

3(20%)

 

Lauren classification

0.657

 Intestinal

16(50.0%)

5(31.3%)

 

 Diffuse

11(34.4%)

2(18.1%)

 

 Mixed

5(15.6%)

2(40%)

 

Pre-surgery chemotherapy

 

0.382

 yes

9(28.1%)

1(11.1%)

 

 no

23(71.9%)

8(34.8%)

 
  1. aP values are from Fisher’s exact test and were significant at <0.05.undiff,undifferentiated