Fig. 3

Cumulative incidence of deaths in elderly CLL patients vs. younger patients. CIF of CLL-related deaths stratified by age in a LOT1 and b LOT ≥ 2, and CLL- or infection-related deaths stratified by age in c LOT1 and d LOT ≥ 2, demonstrating increased mortality in elderly CLL patients (red line). Horizontal dashed line shows median survival in patients ≥ 75 years. CI confidence interval, CIF cumulative incidence functions, CLL chronic lymphocytic leukemia, LOT1 first line of therapy, LOT ≥ 2 second line of therapy or greater