Patients with pathological stage N2 rectal cancer treated with early adjuvant chemotherapy have a lower treatment failure rate

Table 2 Failure patterns of patients with pathological stage N2 rectal cancer in A-CRT group and A-CT group

Sites of recurrence	A-CRT group		A-CT group		p
Sites of recurrence	n	%	n	%	p
Total no. of recurrence	24	33.8	7	16.3	0.042
No. of locoregional recurrence	4	5.6	1	2.3	0.647
No. of distant metastasis	23	32.4	6	14.3	0.028
All site of distant metastasis
Lung	14		3
Liver	7		1
Bone	3		1
Non-regional lymph nodes	3		1
Peritoneal seeding	2		1

Abbreviations: A-CRT primary adjuvant concurrent chemoradiotherapy, A-CT primary adjuvant chemotherapy

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