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Fig. 4 | BMC Cancer

Fig. 4

From: miR-124 targets GATA6 to suppress cholangiocarcinoma cell invasion and metastasis

Fig. 4

miR-124 inhibits CCA cell invasion and metastasis by downregulating GATA6. a, b Validation of miR-124 and GATA6 levels after transfection. c, d Remedial expression of GATA6 significantly abrogated the miR-124-induced suppression of QBC939 cell invasion and migration in Transwell and wound healing assays. e IHC analysis of GATA6 expression in the liver masses of xenotransplanted mice. f Validation of miR-124 expression in the liver masses. Ex-miR-124: CCA cells transfected with miR-124 mimics. *P < 0.05

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