First insight into the somatic mutation burden of neurofibromatosis type 2-associated grade I and grade II meningiomas: a case report comprehensive genomic study of two cranial meningiomas with vastly different clinical presentation

Table 1 Grade II meningioma chromosomal aberrations identified by SNP-array analysis

Chromosome	Mutation	Location	Previously reported?
1	Loss	p36.33 to p34.2	Yes
	Loss	p33 to p31.3	Yes
	Gain	p31.3 to p31.1	No
	Loss	p31.1	Yes
	Loss	p31.1 to p22.3	Yes
	Loss	p22.1 to p13.2	Yes
	Gain	q21.2 to q21.3	Yes
	Gain	q21.3 to q42.13	Yes
2	Loss	p23.2	Yes
2	Loss	q22.1	Yes
3	Loss	p14.2	Yes
	Gain	p14.2	No
	Loss	q26.31	Yes
6	Loss	q12	Yes
6	Loss	q13-q27	Yes
7	Gain	q11.21	No
11	Loss	p15.5 to p15.4	No
12	Loss	p13.33 to p11.21	Yes
14	Loss	q31.1	Yes
18	Loss	q23	Yes
22	Loss	q11.23-q13.33	Yes
X	Loss	p21.1	Yes

ISSN: 1471-2407