Table 3 Top 50 most differentially expressed annotated genes in H. felis-infected Myd88 −/− mice at 47 weeks compared to uninfected controls
Gene Symbol | Gene Name | LogFC | Adj. P.Val |
|---|---|---|---|
Chil4 | chitinase-like 4 | 4.97 | 1.24E-03 |
Cd74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) | 4.18 | 7.41E-08 |
Bpifb1 | BPI fold containing family B, member 1 | 4.02 | 6.43E-04 |
H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 3.96 | 4.14E-07 |
Ido1 | indoleamine 2,3-dioxygenase 1 | 3.78 | 1.44E-04 |
Igtp | interferon gamma induced GTPase | 3.29 | 1.25E-04 |
Sftpd | surfactant associated protein D | 3.24 | 4.86E-07 |
H2-DMb2 | histocompatibility 2, class II, locus Mb2 | 3.20 | 4.43E-06 |
Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 3.20 | 1.71E-06 |
Gbp2 | guanylate binding protein 2 | 3.15 | 4.53E-05 |
H2-DMa | histocompatibility 2, class II, locus DMa | 3.13 | 2.17E-05 |
H2-Eb1 | histocompatibility 2, class II antigen E beta | 3.05 | 6.39E-06 |
Ubd | ubiquitin D | 2.85 | 8.22E-05 |
B2m | beta-2 microglobulin | 2.81 | 4.14E-07 |
H2-K2 | histocompatibility 2, K region locus 2 | 2.58 | 7.37E-07 |
H2-Aa | histocompatibility 2, class II antigen A, alpha | 2.56 | 1.39E-05 |
Irgm2 | immunity-related GTPase family M member 2 | 2.53 | 5.62E-05 |
H2-DMb1 | histocompatibility 2, class II, locus Mb1 | 2.47 | 5.72E-06 |
H2-K1 | histocompatibility 2, K1, K region | 2.40 | 3.89E-06 |
Serpina3g | serine (or cysteine) peptidase inhibitor, clade A, member 3G | 2.30 | 4.90E-06 |
Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 2.30 | 4.92E-05 |
Psmb10 | proteasome (prosome, macropain) subunit, beta type 10 | 2.29 | 1.49E-05 |
Pigr | polymeric immunoglobulin receptor | 2.29 | 2.37E-05 |
Oasl2 | 2′-5′ oligoadenylate synthetase-like 2 | 2.24 | 6.52E-04 |
H2-Q7 | histocompatibility 2, Q region locus 7 | 2.22 | 4.90E-06 |
Casp1 | caspase 1 | 2.20 | 1.33E-04 |
Irf1 | interferon regulatory factor 1 | 2.17 | 8.33E-05 |
C3 | complement component 3 | 2.15 | 4.52E-05 |
Cxcl9 | chemokine (C-X-C motif) ligand 9 | 2.14 | 1.04E-04 |
Pkp4 | plakophilin 4 | 2.11 | 1.28E-05 |
Rnf213 | ring finger protein 213 | 2.08 | 1.59E-04 |
H2-D1 | histocompatibility 2, D region locus 1 | 2.04 | 2.78E-06 |
Ear2 | eosinophil-associated, ribonuclease A family, member 2 | 2.04 | 9.57E-04 |
Sst | somatostatin | −2.01 | 1.25E-04 |
Smim24 | small integral membrane protein 24 | −2.11 | 3.12E-05 |
Muc5ac | mucin 5, subtypes A and C, tracheobronchial/gastric | −2.23 | 1.14E-03 |
Lpl | lipoprotein lipase | −2.32 | 3.50E-04 |
Sgk1 | serum/glucocorticoid regulated kinase 1 | −2.33 | 8.22E-05 |
Ckb | creatine kinase, brain | −2.35 | 1.02E-04 |
Gif | gastric intrinsic factor | −2.36 | 3.50E-04 |
Cox7a1 | cytochrome c oxidase subunit VIIa 1 | −2.49 | 1.06E-04 |
Ttr | transthyretin | −2.57 | 9.85E-06 |
Dpcr1 | diffuse panbronchiolitis critical region 1 (human) | −2.57 | 1.05E-03 |
Fabp3 | fatty acid binding protein 3, muscle and heart | −2.61 | 6.23E-05 |
Atp4a | ATPase, H+/K+ exchanging, gastric, alpha polypeptide | −2.95 | 6.99E-04 |
Apoa1 | apolipoprotein A-I | −3.13 | 1.23E-03 |
Hamp2 | hepcidin antimicrobial peptide 2 | −3.45 | 1.25E-04 |
Pdia2 | protein disulfide isomerase associated 2 | −3.57 | 7.21E-06 |
Amy2a5 | amylase 2a5 | −4.09 | 1.74E-04 |
Chia1 | chitinase, acidic 1 | −5.25 | 6.66E-04 |