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Table 3 Agreement table at the mutation specific level

From: Clinical performance evaluation of a sensitive, rapid low-throughput test for KRAS mutation analysis using formalin-fixed, paraffin-embedded tissue samples

Idylla™

G12A

G12C

G12D

G12R

G12S

G12V

G13D

No mutation detected

Invalid

A59E/P/V

Q61H/H2

Q61K/K2

Q61L/R

K117N1/N2

A146T/V/0

Total

therascreen

                

12ALA

6

      

1a

       

7

12CYS

 

6

           

1

 

7

12ASP

  

25

            

25

12ARG

   

3

           

3

12SER

    

6

1

1

        

8

12VAL

     

15

  

1

     

1

17

13ASP

      

16

        

16

No mutation detected

   

1a

 

1a

3a

97

 

1

3

  

2

4

112

Invalid/Run Control failed

 

2

1

 

3

2

1

41

6

     

1

57

Total

6

8

26

4

9

19

21

139

7

1

3

0

0

3

6

252

  1. Genotyping concordance between the Idylla™ test and the reference test. Italic: discordant by design specimens. a True discordant samples. Bold: mutant-mutant discordant results
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BMC Cancer

ISSN: 1471-2407

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