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Table 1 List of predicted transcription factors (TFs) associated with docetaxel-resistance

From: The prognostic utility of the transcription factor SRF in docetaxel-resistant prostate cancer: in-vitro discovery and in-vivo validation

Symbol of predicted target Description RefSeq Accession Log (Fold Change) P-Value
NFKB2 Nuclear factor of Kapa Light Polypeptide gene enhancer in B-cells 2 NM 002502 −0.769367 0.000829
SRF c-fos serum response element-binding transcription factor NM_003131 0.830936 0.000984
TR2 nuclear receptor subfamily 2, group C, member 1 NM_003297.3 0.93892 0.000149
TR4 nuclear receptor subfamily 2, group C, member 2 NM_003298.3 −2.117639 1.54E-05
NR1H2 nuclear receptor subfamily 1, group H, member 2 NM_007121 2.086756 1.36E-05
BRN5 POU domain, class 6, transcription factor 1 NM_002702.3 1.090898 0.011998
PPAR_RXR peroxisome proliferator-activated receptor alpha NM_001001928.2 −0.570508 0.025654
ER estrogen receptor 1 NM_000125.3 1.7681357 8.57E-06
NFE2L2 nuclear factor (erythroid-derived 2)-like 2 NM_001145412.2 0.415401 0.010718
  1. Transcriptomic data was integrated with known and predicted transcription factor binding sites (TFBS) resulting in a list of transcription factors (TFs) associated with the differential gene expression observed with the transcriptomic profiling