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Fig. 3 | BMC Cancer

Fig. 3

From: Enhanced and long term immunogenicity of a Her-2/neu multi-epitope vaccine conjugated to the carrier CRM197 in conjunction with the adjuvant Montanide

Fig. 3

Levels of serum IgG, IgG1 and IgG2a antibody responses against P467 and recombinant extracellular Her-2/neu. The levels of serum IgG, IgG1 and IgG2a against P467 (3a, 3b and 3c) or recombinant extracellular Her-2/neu (3d, 3e and 3f), induced after 3 immunizations with different concentrations of the conjugate administered with Alum or Montanide, are shown. The OD values are based on ELISA experiments as described in materials and methods. The statistical analysis was performed using ANOVA (two-way) and linear contrasts. Significant differences are denoted by asterisks. ns, not significant

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