Treatment | ||||
---|---|---|---|---|
Chemotherapy n = 32a | Chemotherapy plus radiotherapy n = 17b | |||
Variables | Normal | Overweigth/Obese | Normal | Overweigth/Obese |
n: number (%) | 17 | 15 (47) | 12 | 5 (29) |
Sex (M) | 12 | 12 | 9 | 4 |
Current age (Y) | 12.1 (8.1, 17.0) | 12 (7.1, 17.0) | 12.6 (7.1, 16.1) | 12.1 (8.0, 17.1) |
Age at cancer diagnosis (Y) | 6.0 (2.0, 13.0) | 4.0 (2.0, 12.1) | 6.5 (0.08, 12.1) | 7 (1.0, 11.1) |
Time since completion of therapy (Y) | 4.0 (2.0, 5.1) | 4.0 (2.1, 5.1) | 3.1 (3.0, 5.0) | 4.0 (2.0, 5.0) |
Weight (kg) | 46.9 (18.1, 91.2) | 48.9 (26.2, 102.9) | ||
Height (cm) | 148.4 (116.2, 178) | 157.9 (123, 176.1) | ||
Diagnosis : ALL/Lymphoma | 11/6 | 9/6 | 4/8 | 1/4 |
Pubertal stage | ||||
1 | 9 | 13* | 5 | 3 |
≥ 2 | 8 | 2 | 7 | 2 |
MS Components | ||||
WC (pc) | 25 (10, 75) | 90 (50, 100)* | 50 (10, 90) | 90 (75, 100) |
SBP (pc) | 47 (3, 92) | 53 (18, 93) | 17 (2, 65) | 47 (20, 99) |
DBP (pc) | 76 (15, 94) | 82 (57, 99) | 75 (19, 96) | 89 (39, 99) |
Triglicerydes (mg/dL) | 76 (34, 149) | 114 (50, 231) | 72 (35, 164) | 188 (148, 210) |
HDL-C (mg/dL) | 42 (25, 84) | 39.5 (26, 78) | 42 (18, 64) | 43 (18, 48) |
Glucose (mg/dL) | 90 (75.5, 115.7) | 91 (76, 105.7) | 86 (74, 112.5) | 93 (82, 99) |
Others metabolic variables | ||||
Insulin (μU/mL) | 16.3 (9.1, 38.7) | 24.9 (14.2, 35.3)* | 20.5 (4.3, 50) | 36.3 (19, 55) |
HOMA-IR | 3.6 (1.7, 9.5) | 5.5 (2.8, 8.2)* | 4.3 (0.79, 13.9) | 8.3 (4.7, 12.7) |
Adiponectin (μg/mL) | 23 (1.3, 44.3) | 22 (6.8, 70) | 19.1 (11.7, 41.2) | 16 (1.3, 27.6) |
Adiponectin per Kg fat (μg/mL/kg) | 1.5 (0.39, 6.7) | 1.2 (0.28, 4.9) | 1.8 (0.51, 5.1) | 0.75 (0.7, 1.8) |
Leptin ((μg/mL) | 4.4 (2, 13.4) | 18.2 (9.8, 30.9)* | 7.4 (1.2, 19.0) | 17.5 (13.5, 18.5) |
Leptin per Kg fat (μg/mL/kg) | 0.49 (0.11, 3.0) | 1.0 (0.34, 3.7)* | 0.46 (0.16, 3.9) | 0.72 (0.53, 1.31) |
Leptin to Adiponectin ratio | 0.27 (0.08, 2.7) | 0.98 (0.20, 3.0)* | 0.33 (0.06, 0.76) | 0.85 (0.67, 11.0) |
Body Fat (%) | 23.4, (9.9, 36.2) | 38.3 (32.0, 46.7)* | 27.4 (8.3, 38.1) | 37.1 (28.5, 40.2) |
VCAM (ng/mL) | 1058 (561, 1727) | 818 (425, 1730) | 856 (586, 1207) | 989 (490, 1697) |
ICAM (ng/mL) | 459 (254, 661) | 418 (294, 1079) | 500 (265, 952) | 398 (324, 598) |
MS | ||||
Yes/No | 0/17 | 4/11 | 1/11 | 2/3 |