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Table 1 Top Commonly Regulated Genes between LNCaP MVs and PC-3 MVs vs PNT2 MVs

From: Distinct prostate cancer-related mRNA cargo in extracellular vesicle subsets from prostate cell lines

    

LNCaP MVs

PC-3 MVs

Gene Symbol

Name

Unigene ID

RefSeq

Log FC

P Value

Log FC

P Value

Up-regulated

 ETV1

Ets variant 1

Hs.574240

NM_004956

4.3

0.042

3.4

0.02

 FASN

Fatty acid synthase

Hs.83190

NM_004104

5.3

0.016

5.8

0.01

 RBM39

RNA binding motif protein 39

Hs.282901

NM_004902

4.7

0.027

5.3

<0.001

Down-regulated

 CCND2

Cyclin D2

Hs.376071

NM_001759

−7.7

0.030

−6.2

0.031

 ERG

V-ets erythroblastosis virus E26 oncogene homolog (avian)

Hs.473819

NM_182918

−4.3

0.049

−7.3

0.041

 GNRH1

Gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)

Hs.82963

NM_000825

−4.0

0.029

−4.5

0.024

 HAL

Histidine ammonia-lyase

Hs.190783

NM_002108

−5.7

<0.001

−6.3

<0.001

 LGALS4

Lectin, galactoside-binding, soluble, 4

Hs.5302

NM_006149

−4.1

0.034

−3.6

0.037

  1. Log2 fold-change (mean of the differential mRNA levels); P value for the differential mRNA levels