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Table 1 Top Commonly Regulated Genes between LNCaP MVs and PC-3 MVs vs PNT2 MVs

From: Distinct prostate cancer-related mRNA cargo in extracellular vesicle subsets from prostate cell lines

     LNCaP MVs PC-3 MVs
Gene Symbol Name Unigene ID RefSeq Log FC P Value Log FC P Value
Up-regulated
 ETV1 Ets variant 1 Hs.574240 NM_004956 4.3 0.042 3.4 0.02
 FASN Fatty acid synthase Hs.83190 NM_004104 5.3 0.016 5.8 0.01
 RBM39 RNA binding motif protein 39 Hs.282901 NM_004902 4.7 0.027 5.3 <0.001
Down-regulated
 CCND2 Cyclin D2 Hs.376071 NM_001759 −7.7 0.030 −6.2 0.031
 ERG V-ets erythroblastosis virus E26 oncogene homolog (avian) Hs.473819 NM_182918 −4.3 0.049 −7.3 0.041
 GNRH1 Gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) Hs.82963 NM_000825 −4.0 0.029 −4.5 0.024
 HAL Histidine ammonia-lyase Hs.190783 NM_002108 −5.7 <0.001 −6.3 <0.001
 LGALS4 Lectin, galactoside-binding, soluble, 4 Hs.5302 NM_006149 −4.1 0.034 −3.6 0.037
  1. Log2 fold-change (mean of the differential mRNA levels); P value for the differential mRNA levels
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BMC Cancer

ISSN: 1471-2407

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