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Table 4 Associations of percent mammographic breast density (PD) with breast cancer risk in a subgroup of women with atypical hyperplasia

From: Mammographic breast density and risk of breast cancer in women with atypical hyperplasia: an observational cohort study from the Mayo Clinic Benign Breast Disease (BBD) cohort

Characteristic

No. Women

Person Years

Observed Events

Expected Events

SIR (95% CI)

p-valuea

Overall

212

2469

32

10.15

3.15 (2.16, 4.45)

 

Percent Density

     

0.76

 0-10%

59

688

8

3.15

2.54 (1.10, 5.00)

 

 11-25%

69

777

12

3.20

3.75 (1.94, 6.55)

 

 26-50%

76

900

10

3.41

2.94 (1.41, 5.40)

 

 51 + %

8

104

2

0.40

4.98 (0.60, 17.92)

 
  1. Standardized incidence ratios and corresponding 95% confidence intervals, comparing the observed number of breast cancer events to those expected based on incidence rates from Iowa SEER data
  2. Analyses account for the effects of age and calendar period
  3. a P-value, test of heterogeneity in SIRs