| Low Density | Medium Density | High Density | p-valuea | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Characteristic | N | Obs | Exp | SIR (95% CI) | N | Obs | Exp | SIR (95% CI) | N | Obs | Exp | SIR (95% CI) | |
Overall | 69 | 12 | 3.53 | 3.40 (1.76, 5.93) | 231 | 41 | 11.77 | 3.48 (2.50, 4.73) | 170 | 29 | 8.92 | 3.25 (2.18, 4.67) | 0.96 |
Type of Density Measure | |||||||||||||
 PPAT | 60 | 11 | 3.16 | 3.48 (1.74, 6.23) | 91 | 17 | 5.39 | 3.15 (1.84, 5.05) | 131 | 24 | 7.33 | 3.28 (2.10, 4.87) | 0.97 |
 BIRADS | 9 | 1 | 0.37 | 2.73 (0.07, 15.13) | 140 | 24 | 6.37 | 3.77 (2.41, 5.60) | 39 | 5 | 1.59 | 3.14 (1.02, 7.31) | 0.89 |
Age at Biopsy | |||||||||||||
  < 45 | 7 | 2 | 0.30 | 6.61 (0.80, 23.79) | 15 | 2 | 0.32 | 6.17 (0.75, 22.21) | 32 | 4 | 1.20 | 3.33 (0.91, 8.53) | 0.66 |
 45-55 | 9 | 0 | 0.39 | NA | 76 | 15 | 3.64 | 4.12 (2.31, 6.80) | 67 | 14 | 3.65 | 3.84 (2.10, 6.44) | 0.21 |
 55+ | 53 | 10 | 2.84 | 3.53 (1.69, 6.49) | 140 | 24 | 7.80 | 3.08 (1.97, 4.58) | 71 | 11 | 4.07 | 2.70 (1.35, 4.84) | 0.83 |
Number of Atypical Foci | |||||||||||||
 1 | 47 | 6 | 2.73 | 2.20 (0.81, 4.79) | 126 | 19 | 6.80 | 2.79 (1.68, 4.36) | 96 | 16 | 4.76 | 3.36 (1.92, 5.46) | 0.65 |
 2 | 15 | 4 | 0.52 | 7.73 (2.11, 19.81) | 61 | 14 | 2.81 | 4.98 (2.72, 8.36) | 42 | 6 | 2.42 | 2.48 (0.91, 5.40) | 0.16 |
 3+ | 7 | 2 | 0.29 | 6.98 (0.84, 25.13) | 44 | 8 | 2.15 | 3.72 (1.61, 7.32) | 32 | 7 | 1.74 | 4.03 (1.62, 8.29) | 0.76 |
Type of Atypia | |||||||||||||
 ADH | 41 | 7 | 2.18 | 3.21 (1.29, 6.61) | 116 | 17 | 5.74 | 2.96 (1.73, 4.75) | 65 | 15 | 3.48 | 4.31 (2.41, 7.11) | 0.57 |
 ALH | 27 | 5 | 1.28 | 3.92 (1.27, 9.12) | 96 | 20 | 5.14 | 3.89 (2.38, 6.01) | 96 | 13 | 4.92 | 2.64 (1.40, 4.52) | 0.51 |
 ADH and ALH | 1 | 0 | 0.08 | NA | 19 | 4 | 0.89 | 4.48 (1.22, 11.48) | 9 | 1 | 0.51 | 1.94 (0.05, 10.79) | 0.56 |
BMI at Biopsy | |||||||||||||
  < 25 | 25 | 2 | 1.45 | 1.38 (0.17, 4.97) | 78 | 18 | 3.96 | 4.55 (2.69, 7.19) | 101 | 17 | 5.17 | 3.29 (1.91, 5.27) | 0.16 |
 25-29 | 19 | 5 | 1.01 | 4.96 (1.61, 11.55) | 70 | 10 | 3.37 | 2.97 (1.42, 5.46) | 35 | 4 | 1.95 | 2.05 (0.56, 5.25) | 0.42 |
 30+ | 24 | 5 | 1.07 | 4.66 (1.51, 10.86) | 81 | 13 | 4.39 | 2.96 (1.57, 5.07) | 32 | 7 | 1.76 | 3.97 (1.60, 8.17) | 0.65 |