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Table 3 Data collection time point of all outcome measures and proposed mediators

From: Study protocol of the TIRED study: a randomised controlled trial comparing either graded exercise therapy for severe fatigue or cognitive behaviour therapy with usual care in patients with incurable cancer

Concept Questionnaire Measurement time points
T0 T1 T2 T3
Socio-demographics Self-report questionnaire X    
Medical characteristics Medical chart review X X   
Primary outcome:
Fatigue severity CIS fatigue severity X X X X
Secondary outcomes:
Fatigue EORTC QLQ-C30 fatigue X X X X
Quality of life EORTC QLQ-C30 global health status X X X X
Functional impairments SIP X X X X
  EORTC QLQ-C30 emotional functioning X X X X
  EORTC QLQ-C30 physical functioning X X X X
Proposed mediators:
Physical activity Actigraphy during 12 consecutive days X X   
Physical fitness 6MWT X X   
Self-efficacy SES X X   
Fatigue catastrophising FCS X X   
  1. T0 baseline (pre-intervention), T1 post-intervention/UC (14 weeks post-randomisation), T2 first follow-up assessment (18-weeks post-randomisation), T3 s follow-up assessment (26-weeks post-randomisation)